Thyroid
Overview

Thyroid nodules are solid or fluid-filled lumps that form within thyroid, a small gland located at the base of neck, just above breastbone. 

Symptom

Most thyroid nodules don’t cause signs or symptoms. But occasionally some nodules become so large that they can:

● Be felt
● Be seen, often as a swelling at the base of your neck
● Press on windpipe or esophagus, causing shortness of breath or difficulty swallowing


In some cases, thyroid nodules produce additional thyroxine, a hormone secreted by thyroid gland. The extra thyroxine can cause symptoms of an overproduction of thyroid hormones (hyperthyroidism), such as:

● Unexplained weight loss
● Increased sweating
● Tremor
● Nervousness
● Rapid or irregular heartbeat


Only a small number of thyroid nodules are cancerous. But determining which nodules are cancerous can’t be done by evaluating symptoms alone. Most cancerous thyroid nodules are slow growing and may be small when the doctor discovers them. Aggressive thyroid cancers are rare with nodules that may be large, firm, fixed and rapid growing.

Treatment
Ultrasound (US)-guided radiofrequency ablation (RFA) for thyroid lesions is a minimally invasive treatment modality, as an alternative to surgery in patients with benign thyroid nodules and recurrent thyroid cancers. RFA has shown good efficacy and safety in the management of thyroid nodule related cosmetic problems and pressure symptoms.